Jason Ernst
Professor
Develops machine learning methods for epigenomics, such as ChromHMM for chromatin state annotation.
Jason Ernst's lab at UCLA works on genomics & computational biology and proteins, drugs & materials. 25 papers since 2023, 3 at top venues, mostly Bioinformatics and Cell. 2 PhD students. 21 alumni, most often to NVIDIA. Applications close .
At a glance
- papers, 2023–2026
- 7/ year
- at T1 venues
- 12%
- PhD students
- 2
- MS students
- 0
- alumni listed
- 21
Papers by yearfrom the lab homepage, 2023–2026
- 7 papers2026 · T1 0 · collecting
- 6 papers2025 · T1 1
- 4 papers2024 · T1 1
- 8 papers2023 · T1 1
T1 venuesOtherVenues: Bioinformatics, Cell, Nature, Science
Research focuspaper titles that use each topic's words
- state5 papers
- Genomics & computational biology3 papers
- annotation2 papers
- biological1 paper
- Proteins, drugs & materials0 papers
Paper list
From the lab homepage.
20267 papers
- Genome BiologyGECSI: large-scale chromatin state imputation from gene expression (opens in a new tab)
- Genome BiologyHi-C derived insulation strength predicts evolutionary conservation of topologically associating domains (opens in a new tab)
- BioinformaticsLearning a Pairwise Epigenomic and Transcription Factor Binding Association Score Across the Human Genome (opens in a new tab)
- Bioinformaticsmap3C: a computational tool for processing multiomic single-cell Hi-C data (opens in a new tab)
- Genome BiologyMissenseHMM: state-based annotations for missense variants through joint modeling of pathogenicity scores (opens in a new tab)
- HGG AdvancesWhole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia (opens in a new tab)
- Epigenetics & ChromatinWhole-genome 5-hydroxymethylation profiling of human neurons for regulatory and biological insight (opens in a new tab)
20256 papers
- Genome BiologyChromActivity: integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types (opens in a new tab)
- Genome BiologyCMImpute: cross-species and tissue imputation of species-level DNA methylation samples across mammalian species (opens in a new tab)
- Cell (T1)Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice (opens in a new tab)
- Communications BiologyGenome-wide identification and analysis of recurring patterns of epigenetic variation across individuals (opens in a new tab)
- Genome BiologyIdentifying associations of de novo noncoding variants with autism through integration of gene expression, sequence, and sex information (opens in a new tab)
- Bioinformatics AdvancesPerspective on recent developments and challenges in regulatory and systems genomics
20244 papers
- Cell Stem CellAlternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation (opens in a new tab)
- Cell GenomicsComplementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior (opens in a new tab)
- Nature (T1)Deciphering the impact of genomic variation on function (opens in a new tab)
- Science AdvancesEpigenetic predictors of species maximum life span and other life-history traits in mammals (opens in a new tab)
20238 papers
- BioinformaticsA framework for group-wise summarization and comparison of chromatin state annotations (opens in a new tab)
- Genome BiologyChromGene: gene-based modeling of epigenomic data (opens in a new tab)
- Science (T1)DNA methylation networks underlying mammalian traits (opens in a new tab)
- —Geroscience, 45:3187-3209, 2023
- Cell GenomicsSingle-cell methylation analysis of brain tissue prioritizes mutations that alter transcription (opens in a new tab)
- Aging CellSTAT3 promotes a youthful epigenetic state in articular chondrocytes (opens in a new tab)
- Genome BiologyUniversal chromatin state annotation of the mouse genome (opens in a new tab)
- Nature AgingUniversal DNA methylation age across mammalian tissues (opens in a new tab)
Where alumni went21 listed, 50% to industry
Industry 1Academia 1
Most often to
- NVIDIA
Also to
- Ellison Institute of Technology
Apply to UCLAFall 2027
Computer Science PhD
- Round
- Single round (Dec 15)
- Opens
- —
- GRE
- optional
- English
- See program page
- Fee
- See program page
Not yet confirmed for this intake.
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7 T1
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